Apple on Wednesday morning released a fifth beta of iOS 10.1 for the iPhone 7 and iPhone 7 Plus only. The latest beta came out two days after the release of iOS 10.1 beta 4 on Monday.
iOS 10.1 beta 5 is available as an over-the-air download on an iPhone 7 or iPhone 7 Plus with a prior beta. Today's iPhone 7-focused release likely contains a cellular connectivity bug that Apple patched with an emergency update on October 17. macOS Sierra 10.12.1 beta 5 also released today.